货号价格

CD7-HM401P-100μg / 询价

CD7-HM401P-500μg / 询价

CD7-HM401P-500μgx2 / 询价

PE-Labeled Human CD7 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant PE-Labeled Human CD7 Protein is expressed from HEK293 His tag and Avi tag at the C-Terminus. It contains Ala26-Pro180.[Accession | P09564]

分子量大小(Molecular Weight)

The protein has a predicted MW of 19.3 kDa.

波长(Wavelength)

Excitation Wavelength: 488 nm / 561 nm

Emission Wavelength: 575 nm

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 6 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
ELISA Data

Immobilized PE-Labeled Human CD7, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD7 Antibody, hFc Tag with the EC50 of 9.2ng/ml determined by ELISA.

背景(Background)

CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells.

分子别名(Synonyms)

CD7 molecule; CD7; LEU-9; Tp40; TP41; GP40

文献(References)

(1)Gomes-Silva D , Srinivasan M , Sharma S , et al. CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies[J]. Blood, 2017:blood-2017-01-761320.